
Collagen is a protein that is naturally abundant in the body, and it gives our skin its firmness and radiance. Although we often talk about collagen in the singular, it would be more accurate to talk about collagens in the plural. Indeed, there are 29 different types of collagens in the human body, each with its own structure and function.
To compensate for the decrease in collagen linked to aging, many collagen-based food supplements are available on the market. But then, which collagen to choose?
Whether it is marine collagen, collagen peptides or hydrolyzed collagen, it can be difficult to make an informed choice and to decode the labels.
Whether you are a novice or passionate about skincare looking for detailed advice, this article is here for you.
We will review the different types of collagen and provide you with wise advice on choosing the best form for you that will best suit your needs. We will also focus on the best hydrolyzed marine collagen treatments with low molecular weight.
Also read: what is collagen and The benefits of collagen for health
Summary
I. Understanding Collagen: Origins and Types
Collagen is an essential protein found in different parts of the human body, including skin, bones, tendons, ligaments and blood vessels. It is also found in some foods.
"Today, we are aware of 29 different types of collagen, including 12 in the skin, but then, which collagen should we choose?"
Collagens present in the body are classified into several types depending on their structure, size and role.
Among these types, the most abundant in the human body are collagen types 1, 2, 3 and 4. Each of these types performs specific functions in the body.
To choose which collagen is best suited, it is important to consider different factors such as the source, the quality, and the biodisponibility of collagen.
Traditionally, collagen was extracted from animal sources such as skin, bones and tendons.
However, with changing ethical preferences and the search for new alternatives, new sources of collagen have emerged.
Some collagen dietary supplements now use alternative sources such as marine collagen, which is extracted from fish, or vegan collagen, which is derived from plant proteins.
These new sources meet the needs of people with specific ethical or dietary concerns.
It is also important to check the quality of the collagen. Look for reputable brands that use rigorous extraction and processing methods to obtain pure, high-quality collagen.
Bioavailability is another key factor to consider. Bioavailability refers to the ability of a dietary supplement to be absorbed and utilized by the body.
Some collagens have better bioavailability than others due to their size and structure.
It is recommended to consult a healthcare professional or nutritionist for personalized advice on which collagen to choose based on your specific needs and concerns.
They will be able to assess your individual situation and recommend the most appropriate type of collagen supplement for you.
The different sources of collagen
Marine collagen: a natural source rich in peptides
Marine collagen is extracted from the skin, scales and bones of fish. It is often considered one of the purest and most bioavailable sources of collagen.
Marine collagen is particularly rich in type I collagen, which is the most abundant type of collagen in the human body.
It is renowned for its benefits for the skin, particularly for improving elasticity, hydration, and reducing wrinkles. Read also, why take marine collagen?
Bovine collagen: effectiveness and bioavailability
Bovine collagen is extracted from the skin, bones and muscles of cattle. It is rich in type I and type III collagen.
Bovine collagen is often used for its benefits on joints, bones and skin.
It is also renowned for its ability to support the health of tendons and ligaments.
Marine or bovine collagen: which is the better choice?
The choice between marine collagen and bovine collagen primarily depends on personal preferences and ethical considerations.
Marine collagen is recognized for its purity and high bioavailability, making it a preferred choice for optimal absorption.
To date, no scientific study proves the superiority of one source over another in terms of effectiveness. The key is to choose a high-quality collagen, regardless of its origin.
Also read, the differences between marine and bovine collagen.
Comparison of marine collagen and other sources of collagen
Marine collagen is distinguished by its high bioavailability, which means it is easily absorbed by the body.
Compared to bovine collagen, marine collagen has a smaller molecular structure, making it easier to absorb.
Additionally, marine collagen is often preferred by those following a specific diet or who have ethical concerns regarding terrestrial animal products.
How does marine collagen compare to other sources of collagen?
Marine collagen is distinguished by its high bioavailability, which means it is easily absorbed by the body.
Compared to bovine collagen, marine collagen has a smaller molecular structure, making it easier to absorb.
Additionally, marine collagen is often preferred by those following a specific diet or who have ethical concerns regarding terrestrial animal products.
The different types of collagen and their functions
The human body contains 29 types of collagen, each having a specific role in the organism. The three most frequently mentioned types are type I, type II, and type III, each having a key function for the skin, joints, and tissue flexibility.
Also discover all the effects of collagen on health.
Type I collagen: for skin firmness and elasticity
Type I collagen is the most abundant in our body and is mainly found in the skin, tendons, ligaments, bones, and teeth.
This type of collagen forms strong fibers that give these tissues their structure, strength, and elasticity. It is essential for maintaining the integrity and firmness of the skin, which is why it is particularly targeted in anti-aging dietary supplements and skin care.
Type III collagen: for joint regeneration and skin hydration
Type III collagen often accompanies type I and is found in blood vessels, muscles, and connective tissue. It is particularly useful for the flexibility and resilience of tissues.
This type of collagen supports not only the joints but also the flexibility of muscles and blood vessels, making it an ideal choice for supplements aimed at improving the overall flexibility of the body.
Type II collagen: for joint well-being
Type II collagen is primarily found in cartilage and plays a crucial role in its flexibility and resistance to compression.
It is therefore particularly important to maintain joint health, by preventing the effects of cartilage aging, such as osteoarthritis.
This is why it is often used in supplements dedicated to joint flexibility.
Differences between type 1 and type 2 collagen
Type I collagen is primarily found in the skin, tendons, and bones, providing firmness and elasticity. Type II collagen, on the other hand, is mainly found in cartilage, playing a crucial role in the flexibility and resistance to compression of the joints.
These two types of collagen have distinct but complementary functions, contributing to the overall health of the skin and joints.
II. The different states of collagen
There are different sources of collagen, but also different forms of collagen available for supplementation.
The question is therefore to know which will be the best and most assimilable state when choosing a dietary supplement, based on your needs, in order to know which collagen to choose.
Not all collagens are created equal. Their effectiveness mainly depends on their state and molecular weight, which directly influences their absorption by the body.
The most popular supplements remain hydrolyzed collagen and collagen peptides, like those used by D-LAB.
Hydrolyzed collagen and collagen peptides, champions of bioavailability
Collagen peptides and hydrolyzed collagen are two forms of collagen that have been broken down into smaller fragments.
These two forms of collagen are used in dietary supplements and cosmetic products for their beneficial effects on skin, hair, nails and joints.
Collagen Peptides
Collagen peptides are smaller pieces of collagen protein, resulting from the breakdown of collagen. They are more easily absorbed by the body due to their reduced size. Once absorbed, the amino acids they contain can act as cellular messengers and stimulate the synthesis of new collagen.
Hydrolyzed collagen
Unlike collagen peptides, hydrolyzed collagen is the whole raw collagen that has undergone a hydrolysis process to break it down into smaller collagen peptides.
Hydrolyzed collagen is a treated form of collagen that has undergone an enzymatic process to break it down into smaller peptides.
This facilitates the absorption of collagen by the body.
Hydrolyzed collagen is often used in dietary supplements, beverages, and collagen-rich functional foods to support joint, skin, and hair health.
The molecular weight of hydrolyzed collagen
The advantages of hydrolysis for bioavailability
Hydrolyzed collagen, also known as collagen peptides, is obtained through an enzymatic hydrolysis process that fragments the molecules into small peptides. This transformation significantly improves their bioavailability and intestinal absorption.
Collagen peptides exist with varying molecular weights, generally between 2000 and 6000 daltons (Da). The lower the molecular weight, the more optimal the absorption.
D-LAB selects marine collagen peptides with a molecular weight of 2000 Da, the smallest available, to ensure maximum absorption and enhanced action on the skin and connective tissues.

Solubilized collagen
Solubilized collagen is a liquid form of collagen that is easily absorbed by the body.
It is obtained by a process of fragmentation of native collagen into smaller fragments, which improves its bioavailability.
Solubilized collagen is often used in dietary supplements, topical cosmetics, and skin care products to promote tissue regeneration and improve the appearance of the skin.
Undenatured collagen
Undenatured collagen (type II) is an intact form that retains its original structure. It is primarily used for joint health, not as a source of amino acids to rebuild collagen, but for an immunomodulatory effect.
This mode of action differs from hydrolyzed collagen, which acts directly by providing the cells with the necessary elements for the synthesis of new collagen.
It is extracted from animal connective tissues and is generally used in the pharmaceutical industry for specific medical applications.
At D-LAB, we prioritize marine hydrolyzed collagen at 2000 Da, scientifically recognized for its high absorption and targeted action on the skin, hair, and supporting tissues.
III. Which collagen to choose for health and beauty?
Collagen in nutricosmetics
D-LAB has been a pioneer of collagen in France for 15 years, developing cutting-edge expertise to offer solutions tailored to every need. We have selected high-quality marine collagens, known for their proven effectiveness and optimal absorption.
Collactive®: the iconic anti-aging collagen from D-LAB
The Collactive® is our flagship collagen, composed of 94% type I marine collagen and 6% elastin, sourced from wild fish. This collagen is ideal for advanced anti-aging formulas, with proven clinical results:
- Effectiveness from 2g/day to reduce wrinkles, improve hydration, and enhance skin firmness.
- MSC Certified, ensuring sustainable fishing.
- Optimal molecular weight of 2,000 Da for rapid absorption.
Naticol®: for radiance, anti-spot, and hair
The Naticol marine collagen® is a marine collagen of type I and III, without elastin, sourced from sustainable aquaculture and certified "Friend of the Sea". It primarily acts on skin radiance, anti-spot treatment, and hair health.
- Effectiveness from 2.5g/day for skin radiance and hair health, and at 5g/day for anti-aging and firmness.
- Improves hair and strengthens skin after 8 weeks.
- Molecular weight similar to that of Collactive® (2,000 Da).
HMG® Collagen: for joint well-being
HMG® Collagen combines types I and III and does not contain elastin. Sourced from wild fish, it is specially recommended for joint health, with a solid scientific basis demonstrating its effectiveness.
- Dosed at 4g/day, it supports joint comfort and flexibility.
Discover the D-LAB collagen range
Collagen in cosmetic active
Collagen-based cosmetic ingredients are used for their beneficial properties on the skin. Cosmetic products containing collagen, in the form of peptides or hydrolysates, are designed to strengthen the skin's structure and reduce visible signs of aging.
When applied to the skin, these collagen actives can help improve skin firmness and elasticity, reduce the appearance of wrinkles and fine lines, and promote deeper hydration. They can also stimulate the production of new collagen by skin cells, thus helping to maintain the youth and beauty of the skin.
However, oral collagen works differently: it penetrates the blood and deeply and globally nourishes the dermis, directly targeting the cells.
This In & Out approach is complementary, providing your skin with the best external care and internal benefits for optimal results.
Couple your collagen active ingredient with your food supplement or collagen powder for quality In & Out action.
To conclude, in order to know which collagen to choose, you must already know for which problem you wish to treat. From there, choose the best collagen treatment based on your needs and the explanations we have given you.
How to choose the most suitable collagen supplement?
The choice of collagen supplement depends on your specific needs.
- For an anti-aging action, Collactive® is ideal.
- For skin radiance and hair health, Naticol® is recommended.
- For joint health, Collagen HMG® is the most suitable.
Each formulation is designed to meet specific needs, ensuring optimal effectiveness.
IV. Taking Collagen: Age and Recommendations
Taking collagen after 50: is it too late?
On the contrary, 50 years old is perfectly within the age range to consume collagen, especially the Anti-Age treatments from D-LAB!
Decreases in collagen, elastin and hyaluronic acid give way to sagging skin and wrinkles.
Collagen will fill in your wrinkles and restore firmness to your skin! As for hyaluronic acid, it will hydrate your skin to give your face a plump and dewy appearance.
At what age is it advisable to start a collagen treatment?
By the age of 25, our natural collagen production reaches its peak, but begins to decline at a rate of 1% per year. This phenomenon, initially imperceptible, gradually affects the firmness, elasticity, and hydration of the skin.
- At 25: Adopt a preventive treatment for 3 months, once a year to preserve your youth capital and delay the first signs of aging.
- After 30 years: Needs become clearer. Do 2 treatments of 3 months each year to target the first wrinkles, restore radiance, and maintain skin firmness.
- From 40-50 years old: The marked loss of collagen, elastin, and hyaluronic acid leads to skin laxity and deep wrinkles. Daily intake throughout the year becomes essential to smooth wrinkles, firm the skin, and optimize deep hydration.
Collagen does not bring instant changes, but with regular use, you can see positive results as early as the first month.
V. Choosing the most effective collagen: the promise of D-LAB
The available collagen formats at D-LAB
D-LAB offers collagens in various formats (powders, sticks, shots) to suit consumer preferences.
Proven clinical efficacy
- Collactive® at 2g/day: Reduces wrinkles by 19% in just 28 days and improves firmness and hydration within 8 weeks.
- Naticol® at 2.5g/day: Improves skin radiance and anti-spot effects, strengthens hair from 8 weeks, and acts on firmness starting at 5g/day after 12 weeks.
Innovation continues at D-LAB
D-LAB continues to innovate to develop new formats and technologies to maximize the efficiency of its products.
To read: optimize your collagen treatment and when to take collagen

frequently asked Questions
What is the most effective collagen?
Hydrolyzed marine collagen is often considered the most effective due to its high bioavailability and clinically proven results. However, to ensure its effectiveness, it is essential to choose a collagen that is based on solid clinical studies, proving its actual action on the skin, hair, nails, and joints.
At D-LAB, our hydrolyzed marine collagens are formulated for optimal absorption, with visible results, supported by clinical studies demonstrating their effectiveness from low doses (such as 2g/day). Our collagens are extracted from sustainable sources and processed according to rigorous methods, ensuring their high quality and proven effectiveness. Also, discover all our drinkable collagens and their various active ingredients in our range with the different powdered collagens from D-LAB.
It is crucial to prioritize a high-quality collagen, supported by scientific and clinical research, to ensure visible and lasting results.
What is the difference between type I and type II collagen?
Type I collagen is primarily found in the skin, tendons, and bones, providing firmness and elasticity. Type II collagen, on the other hand, is mainly found in cartilage, playing a crucial role in the flexibility and resistance to compression of the joints. These two types of collagen have distinct but complementary functions, contributing to the overall health of the skin and joints.