Which collagen to choose? The Complete Guide to Collagen Types

which collagen to choose

Collagen is a protein naturally abundant in the body, and it gives our skin its firmness and radiance. Although collagen is often spoken of in the singular, it would be more accurate to speak of collagens in the plural. Indeed, there are 29 different types of collagen in the human body, each having its own structure and function.


To counteract the decrease in collagen related to aging, many collagen-based dietary supplements are available on the market. But then, which collagen to choose?


Whether it's marine collagen, collagen peptides, or hydrolyzed collagen, it can be difficult to make an informed choice and decode the labels.


Whether you are a beginner or passionate about skincare looking for detailed advice, this article is here for you.


We will review the different types of collagen and give you wise advice to choose the best form for you, which will best suit your needs. We will also focus on the best low molecular weight hydrolyzed marine collagen treatments.


Also read: what is collagen and The benefits of collagen on health 

I. Understanding Collagen: Origins and Types

Collagen is an essential protein found in various parts of the human body, including the skin, bones, tendons, ligaments, and blood vessels. It is also present in certain foods.


Today, we know of 29 different types of collagen, including 12 at the skin level, but then, which collagen should we choose?

The collagens present in the body are classified into several types based on their structure, size, and role.

Among these types, the most abundant in the human body are type 1, 2, 3, and 4 collagens. Each of these types performs specific functions in the body.


To choose which collagen is best suited, it is important to consider different factors such as the origin, the quality, and the bioavailability of collagen.


Traditionally, collagen was extracted from animal sources such as skin, bones, and tendons.

However, with the evolution of ethical preferences and the search for new alternatives, new sources of collagen have emerged.


Some collagen dietary supplements now use alternative sources such as marine collagen, which is extracted from fish, or vegan collagen, which is derived from plant proteins.

These new sources meet the needs of people with specific ethical or dietary concerns.


It is also important to check the quality of collagen. Look for reputable brands that use rigorous extraction and processing methods to obtain pure and high-quality collagen.


Bioavailability is another key factor to consider. Bioavailability refers to the ability of a dietary supplement to be absorbed and used by the body.

Some collagens have better bioavailability than others due to their size and structure.


It is recommended to consult a healthcare professional or a nutritionist to obtain personalized advice on which collagen to choose based on your specific needs and concerns.

They will be able to assess your individual situation and recommend the most appropriate type of collagen dietary supplement for you.

The different sources of collagen

Marine collagen: a natural source rich in peptides

Marine collagen is extracted from the skin, scales, and bones of fish. It is often considered one of the purest and most bioavailable sources of collagen.

Marine collagen is particularly rich in type I collagen, which is the most abundant type of collagen in the human body.

It is known for its benefits on the skin, especially for improving elasticity, hydration, and reducing wrinkles. Also read, why take marine collagen?


Bovine collagen: efficacy and bioavailability

Bovine collagen is extracted from the skin, bones, and muscles of cattle. It is rich in type I and type III collagen.

Bovine collagen is often used for its benefits on joints, bones, and skin.

It is also known for its ability to support the health of tendons and ligaments.


Marine or bovine collagen: which is the better choice?

The choice between marine collagen and bovine collagen is primarily based on personal preferences and ethical considerations.

Marine-derived collagen is known for its purity and high bioavailability, making it a preferred choice for optimal absorption. 

To date, no scientific study proves the superiority of one source over another in terms of effectiveness. The essential thing is to choose high-quality collagen, regardless of its origin.

Also read, the differences between marine and bovine collagen.


Comparison of marine collagen and other sources of collagen

Marine collagen is distinguished by its high bioavailability, which means it is easily absorbed by the body.

Compared to bovine collagen, marine collagen has a smaller molecular structure, which facilitates its absorption.

Moreover, marine collagen is often preferred by those who follow a specific diet or have ethical concerns regarding terrestrial animal-derived products.


How does marine collagen compare to other sources of collagen?

Marine collagen is distinguished by its high bioavailability, which means it is easily absorbed by the body.

Compared to bovine collagen, marine collagen has a smaller molecular structure, which facilitates its absorption.

Moreover, marine collagen is often preferred by those who follow a specific diet or have ethical concerns regarding terrestrial animal-derived products.

The different types of collagen and their functions

The human body has 29 types of collagen, each having a specific role in the body. The three most frequently mentioned types are type I, type II, and type III, each having a key function for the skin, joints, and tissue flexibility.

Also discover all the effects of collagen on health.

Type I collagen: for skin firmness and elasticity

Type I collagen is the most abundant in our body and is mainly found in the skin, tendons, ligaments, bones, and teeth. 


This type of collagen forms strong fibers that give these tissues their structure, strength, and elasticity. It is essential for maintaining the integrity and firmness of the skin, which is why it is particularly targeted in anti-aging and skin care supplements.


Type III collagen: for joint regeneration and skin hydration

Type III collagen often accompanies type I and is found in blood vessels, muscles, and connective tissue. It is particularly useful for the flexibility and resilience of tissues. 


This type of collagen supports not only the joints but also the flexibility of muscles and blood vessels, making it an ideal choice for supplements aimed at improving the body's overall suppleness.

Type II collagen: for joint well-being

Type II collagen is mainly present in cartilage and plays a crucial role in its flexibility and resistance to compression


It is therefore particularly important to maintain joint health, by preventing the effects of cartilage aging, such as osteoarthritis. 


That is why it is often used in supplements dedicated to joint flexibility.


Differences between type 1 and type 2 collagen

Type I collagen is mainly found in the skin, tendons, and bones, providing firmness and elasticity. Type II collagen, on the other hand, is primarily located in cartilage, playing a crucial role in the flexibility and compression resistance of joints. 


These two types of collagen have distinct but complementary functions, contributing to the overall health of the skin and joints.

II. The different states of collagen

There are different sources of collagen, but also different usable states of collagen in supplementation

The question is therefore to know which will be the best and most assimilable form when choosing your dietary supplement, depending on your needs, in order to know which collagen to choose. 

Not all collagens are equal. Their effectiveness mainly depends on their condition and molecular weight, which directly influences their absorption by the body.

The most popular supplements remain hydrolyzed collagen and collagen peptides, like those used by D-LAB.

Hydrolyzed collagen and collagen peptides, champions of bioavailability

Collagen peptides and hydrolyzed collagen are two forms of collagen that have been broken down into smaller fragments.

These two forms of collagen are used in dietary supplements and cosmetic products for their beneficial effects on the skin, hair, nails, and joints.


Collagen peptides

Collagen peptides are smaller pieces of collagen proteins, resulting from the breakdown of collagen. They are more easily absorbed by the body due to their reduced size. Once absorbed, the amino acids they contain can act as cellular messengers and stimulate the synthesis of new collagen.


Hydrolyzed collagen

Unlike collagen peptides, hydrolyzed collagen is the whole raw collagen that has undergone a hydrolysis process to break it down into smaller collagen peptides.

Hydrolyzed collagen is a treated form of collagen that has undergone an enzymatic process to break it down into smaller peptides.

This facilitates the absorption of collagen by the body.


Hydrolyzed collagen is often used in dietary supplements, drinks, and collagen-rich functional foods to support the health of joints, skin, and hair.

The molecular weight of hydrolyzed collagen

The benefits of hydrolysis for bioavailability

Hydrolyzed collagen, also called collagen peptides, is obtained through an enzymatic hydrolysis process that breaks down the molecules into small peptides. This transformation significantly improves their bioavailability and intestinal absorption.


Collagen peptides exist with various molecular weights, generally ranging between 2000 and 6000 daltons (Da). The lower the molecular weight, the better the absorption.


D-LAB selects marine collagen peptides with a molecular weight of 2000 Da, the smallest available, to ensure maximum absorption and enhanced action on the skin and connective tissues.

collagen e-book

Solubilized collagen

Solubilized collagen is a liquid form of collagen that is easily absorbed by the body.

It is obtained through a process of breaking down native collagen into smaller fragments, which improves its bioavailability.

Solubilized collagen is often used in dietary supplements, topical cosmetic products, and skin care products to promote tissue regeneration and improve the appearance of the skin.

Undenatured collagen

Undenatured collagen (type II) is an intact form that retains its original structure. It is mainly used for joint health, not as a source of amino acids to rebuild collagen, but for an immunomodulatory effect. 

This mode of action differs from hydrolyzed collagen, which acts directly by providing cells with the elements necessary for the synthesis of new collagen.


It is extracted from animal connective tissues and is generally used in the pharmaceutical industry for specific medical applications.



At D-LAB, we prioritize marine hydrolyzed collagen at 2000 Da, scientifically recognized for its high absorption and targeted action on the skin, hair, and supporting tissues.

III. Which collagen to choose for health and beauty?

Collagen in nutricosmetics

D-LAB has been a pioneer of collagen in France for 15 years, developing cutting-edge expertise to offer solutions tailored to each need. We have selected high-quality marine collagens, known for their proven effectiveness and optimal absorption.


Collactive®: D-LAB's iconic anti-aging collagen

The Collactive® is our flagship collagen, composed of 94% type I marine collagen and 6% elastin, derived from wild fish. This collagen is ideal for advanced anti-aging formulas, with proven clinical results:

  • Effectiveness from 2g/day to reduce wrinkles, improve hydration, and strengthen skin firmness.
  • MSC Certified, guaranteeing sustainable fishing.
  • Optimal molecular weight of 2,000 Da for rapid absorption.

Naticol®: for radiance, anti-spot, and hair

The Naticol marine collagen® is a marine collagen of type I and III, without elastin, sourced from sustainable aquaculture and certified "Friend of the Sea". It mainly acts on skin radiance, anti-spot effects, and hair health.

  • Effectiveness from 2.5g/day for skin radiance and hair health, and at 5g/day for anti-aging and firmness.
  • Improves hair and strengthens skin after 8 weeks.
  • Molecular weight similar to that of Collactive® (2,000 Da).

HMG® Collagen: for joint well-being

The HMG® Collagen combines types I and III and does not contain elastin. Sourced from wild fish, it is specially recommended for joint health, with a strong scientific basis demonstrating its effectiveness.

  • Dosed at 4g/day, it supports joint comfort and flexibility.

Discover the D-LAB collagen range

Collagen as a cosmetic active ingredient

Cosmetic active ingredients based on collagen are used for their beneficial properties on the skin. Cosmetic products containing collagen, in the form of peptides or hydrolysates, are designed to strengthen the skin's structure and reduce visible signs of aging


When applied to the skin, these collagen actives can help improve skin tone and elasticity, reduce the appearance of wrinkles and fine lines, and promote deeper hydration. They can also stimulate the production of new collagen by skin cells, thereby helping to maintain the youthfulness and beauty of the skin.


However, oral collagen works differently: it enters the bloodstream and nourishes the dermis in a deep and comprehensive way, directly targeting the cells. 

This In & Out approach is complementary, offering your skin the best of external care and internal benefits for optimal results.


Pair your collagen asset with your dietary supplement or collagen powder for a quality In & Out action.


To conclude, in order to know which collagen to choose, you first need to know what issue you want to address with a treatment. From there, choose the best collagen treatment based on your needs and the explanations we have given you.

How to choose the most suitable collagen supplement?

The choice of collagen supplement depends on your specific needs. 

  • For an anti-aging action, Collactive® is ideal. 
  • For skin radiance and hair health, Naticol® is recommended. 
  • For joint well-being, Collagène HMG® is the most suitable. 

Each formulation is designed to meet specific needs, ensuring optimal efficiency.

IV. Taking collagen: age and recommendations

Taking collagen after 50 years old: is it too late?

On the contrary, 50 years old is perfectly within the age range to consume collagen, especially the Anti-Age treatments from D-LAB! 


Decreases in collagen, elastin, and hyaluronic acid lead to sagging skin and wrinkles. 

Collagen will fill in your wrinkles and restore firmness to your skin! As for hyaluronic acid, it will hydrate your skin to give your face a plump and full appearance.



From what age is it recommended to start a collagen treatment?

From the age of 25, our natural collagen production reaches its peak but begins to decline at a rate of 1% per year. This phenomenon, initially imperceptible, gradually affects the firmness, elasticity, and hydration of the skin.

  • At 25 years old: Adopt a preventive 3-month treatment once a year to preserve your youthful capital and delay the first signs of aging.
  • After 30 years: Needs become clearer. Do 2 treatments of 3 months per year to target early wrinkles, restore radiance, and maintain skin firmness
  • From 40-50 years old: The marked loss of collagen, elastin, and hyaluronic acid leads to skin sagging and deep wrinkles. A daily intake throughout the year becomes essential to smooth wrinkles, firm the skin, and optimize deep hydration.

Collagen does not bring instant changes, but with regular use, you can observe positive results from the first month.

V. Choosing the most effective collagen: the D-LAB promise

The collagen formats available at D-LAB

D-LAB offers collagens in various formats (powders, sticks, shots) to suit consumer preferences.


Proven clinical efficacy

  • Collactive® at 2g/day: Reduces wrinkles by 19% in just 28 days and improves firmness and hydration from 8 weeks.
  • Naticol® at 2.5g/day: Improves skin radiance and anti-spot effects, strengthens hair from 8 weeks, and acts on firmness from 5g/day after 12 weeks.

Innovation continues at D-LAB

D-LAB continues to innovate to develop new formats and technologies in order to maximize the efficiency of its products.

To read: optimize your collagen treatment and when to take collagen

which collagen to choose

Frequently Asked Questions

What is the most effective collagen?

Hydrolyzed marine collagen is often considered the most effective due to its high bioavailability and clinically proven results. However, to ensure its effectiveness, it is essential to choose a collagen based on solid clinical studies, proving its real action on the skin, hair, nails, and joints.

At D-LAB, our hydrolyzed marine collagens are formulated for optimal absorption, with visible results, supported by clinical studies demonstrating their effectiveness at low doses (such as 2g/day). Our collagens are extracted from sustainable sources and processed using rigorous methods, thus ensuring their high quality and proven effectiveness. Also find all our drinkable collagens and their various active ingredients in our range with the different D-LAB collagen powders.

It is crucial to prioritize high-quality collagen, supported by scientific and clinical research, to ensure visible and lasting results.

What is the difference between type I and type II collagen?

Type I collagen is mainly found in the skin, tendons, and bones, providing firmness and elasticity. Type II collagen, on the other hand, is primarily located in cartilage, playing a crucial role in the flexibility and compression resistance of joints. These two types of collagen have distinct but complementary functions, contributing to the overall health of the skin and joints.

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